Family: Patrick (3rd Earl of Kinghorne &Strathmore) Lyon / Helen Middleton (F48606)
m. 23 Aug 1662
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 | John (2nd Earl of Kinghorn) Lyon (1596-1646)
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 | Elizabeth (of Panmure) Maule ( -1659)
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| Grizel Durham ( -1666)
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| Charles 2nd Earl of Middleton ( -1719)  |
| Lady Grizel Middleton (1640- ) |
| Patrick (3rd Earl of Kinghorne &Strathmore) Lyon (1643-1695)
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| Helen Middleton ( -1708)
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| John (4th Earl of Strathmore) Lyon (1663-1712) |
| Elizabeth (of Strathmore) Lyon ( -1739) |