James married Eliza Fitzhugh Douglas on 7 Oct 1824 in Montgomery Co. Virginia. Eliza (daughter of Capt. James Douglas, Esq. and Sarah Howard Leake) was born in May 1799 in Anson Co., North Carolina, USA; died on 30 Oct 1839 in Montgomery Co. Virginia; was buried on 31 Oct 1839 in Montgomery Co. Virginia. [Group Sheet] [Family Chart]

1. Dr. William Anderson Wade, Dd was born on 2 Aug 1826 in Christianberg, Montgomery Co., Virginia; died on 4 Dec 1893 in Prospect Hill Cemetery, Front Royal, Virginia.
2. Caroline Wade was born on 19 Jul 1828 in Montgomery Co. Virginia; and died.
3. Montague Wade was born on 10 Feb 1830; and died.
4. James Douglas Wade was born on 22 Jul 1832; and died.
5. Sarah Eliza Wade was born on 20 Mar 1834; and died.
6. Hamilton David Wade was born on 27 May 1836; and died.
7. John Taylor Smith Wade was born on 27 Aug 1838; and died.